KLOW vs GLOW: Composition, What the K Adds & Cost
GLOW and KLOW are lyophilized blends that share the same three-peptide base. KLOW adds a fourth peptide, KPV. This guide sets out what is in each vial, what KPV is, how a single-vial blend compares with separate vials, and what each blend costs.
Research use only. Not for human consumption. Not evaluated by Health Canada. This guide covers specifications, storage and documentation. It gives no dosing or usage guidance.
In short.
- GLOW is a 70mg blend of BPC-157, TB-500 and GHK-Cu. KLOW is an 80mg blend of the same three plus KPV (Lys-Pro-Val).
- KPV is a tripeptide matching the last three residues of α-MSH. Its published research is preclinical, mainly in mouse colitis models.
- GLOW is $174.99 and KLOW is $194.99. Both are sold by total fill, so compare components and totals, not assumed ratios.
Side by side.
| Spec | GLOW | KLOW |
|---|---|---|
| Total fill | 70mg blend | 80mg blend |
| Components | BPC-157, TB-500, GHK-Cu | BPC-157, TB-500, GHK-Cu, KPV |
| KPV | Not included | Included |
| Amount of each component | Listed on the COA for your lot | Listed on the COA for your lot |
| Form | Lyophilized powder, one vial | Lyophilized powder, one vial |
| One-time price | $174.99 | $194.99 |
| Blended cost per mg (all components) | $2.50 | $2.44 |
| SKU | VRX-GLOW-OTP | VRX-KLOW-OTP |
Prices in CAD as listed on 26 Sept 2026. Subscription pricing is 15% lower on both. "Blended cost per mg" is an all-components figure: the price divided by total fill, across all components together.
What's the same.
Both blends are built on the same three compounds.
- BPC-157 is a synthetic 15-amino-acid peptide (GEPPPGKPADDAGLV), described in the literature as a stable gastric pentadecapeptide.
- TB-500 is a synthetic peptide based on thymosin β4, a 43-amino-acid protein regarded as the main G-actin-sequestering peptide in mammalian cells. The actin-binding region of thymosin β4 has been studied in short synthetic sequences.
- GHK-Cu is the tripeptide glycyl-L-histidyl-L-lysine bound to copper(II). GHK has a strong affinity for copper and readily forms the GHK-Cu complex, as a 2015 review of GHK biology describes.
Each blend is sold by its total fill: 70mg for GLOW, 80mg for KLOW. For how each component was reported in your vial, read the COA for that lot.
What the K adds.
The K in KLOW stands for KPV, the tripeptide lysine-proline-valine. It corresponds to residues 11 to 13 of α-melanocyte-stimulating hormone (α-MSH), the three amino acids at the C-terminal end of that 13-residue peptide. Its molecular formula is C16H30N4O4 and its molecular weight is 342.43 g/mol.
KPV's research literature is preclinical. The main work is in mouse models of intestinal inflammation:
| Study | Model | What was measured |
|---|---|---|
| Kannengiesser et al., 2008 | DSS-induced colitis and CD45RBhi transfer colitis in mice; mice with a non-functional MC1 receptor | Body weight, colon histology, myeloperoxidase (MPO) activity |
| Dalmasso et al., 2008 | Human intestinal epithelial cell lines and Jurkat T cells in vitro; DSS and TNBS colitis in mice | NF-κB and MAP kinase signalling, cytokine expression, uptake by the PepT1 transporter |
| Laroui et al., 2010 | KPV loaded into nanoparticles; DSS colitis in mice | Inflammatory markers in cells and colon tissue |
In a 2008 study of KPV in mouse colitis models, Kannengiesser and colleagues reported reduced inflammatory infiltrates and lower MPO activity in the DSS model, and effects in MC1R-deficient mice that suggested a mechanism at least partly independent of that receptor. In a 2008 study of PepT1-mediated KPV uptake, Dalmasso and colleagues reported that KPV at nanomolar concentrations inhibited NF-κB and MAP kinase activation in cultured cells, and that uptake ran through PepT1, a di- and tripeptide transporter.
These are cell and animal findings. None of these studies tested KPV in combination with BPC-157, TB-500 or GHK-Cu, so they describe KPV alone, not the KLOW blend.
One vial or separate vials.
Both products are single-vial blends. That design has neutral trade-offs worth weighing against buying single compounds.
| Factor | Single-vial blend | Separate vials |
|---|---|---|
| Lot and COA | One lot code and one COA cover every component | Each compound has its own lot code and COA |
| Ratio | Fixed at manufacture | Set by the researcher |
| Isolating a variable | Not possible within the vial | Each compound can be studied alone |
| Storage window | All components share one clock once reconstituted | Each vial is opened, and its clock started, independently |
| Vials to track | One | Three or four |
Vitaliti's stated window for a reconstituted vial is up to 30 days refrigerated. In a blend, that window applies to every component at once.
Blends also need a COA that accounts for each component, and independent labs report blends in different ways. Some give identity and measured amount for each component; some add a purity figure per component; some give a single blend-average purity and total content alongside measured vs labelled amounts per component. Some labs measure identity and amount only for blends, because the peaks of several peptides can overlap and obscure each other's impurities. The COA for your lot shows how its lab reported each component. BPC-157, TB-500 and GHK-Cu are sold as single vials. KPV is not sold on its own in the current catalogue.
Price and cost per mg.
| GLOW | KLOW | |
|---|---|---|
| Total fill | 70mg | 80mg |
| One-time price | $174.99 | $194.99 |
| Blended cost per mg (all components) | $2.50 | $2.44 |
| Price difference | — | +$20.00 |
Blended cost per mg is a rough guide only. It is an all-components figure, the price divided by total fill across every compound in the vial, and it is not a cost for any one component. The compounds are priced very differently as single vials, so the total says little about any single part of the blend.
The clearer comparison is what each vial contains. KLOW costs $20.00 more than GLOW, holds 80mg in total rather than 70mg, and includes KPV, which GLOW does not.
A note on the name.
"GLOW" is used for several different products online, and not all of them are peptide blends. Some listings under the same name describe unrelated ingredients such as antioxidants or vitamins. Whatever you are comparing, read the component list on the label and the COA for that lot rather than relying on the product name.
Every Vitaliti vial is labelled with its lot code and expiration date. The COA for your lot is available by email on request at contact@vitalitipeptide.com.